Where is corpus striatum located

About Recent Edits Go ad-free. Edit article. View revision history Report problem with Article. Citation, DOI and article data. Jones, J. Corpus striatum. Reference article, Radiopaedia. Central Nervous System. URL of Article. History and etymology The term originates from the Latin "striatus", meaning "striped", referring to the caudatolenticar bridges of grey matter crossing the internal capsule from the putamen to the caudate nucleus 2.

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J Neurosci. People who have written about this concept. Putamen is a round nucleus located at the base of the forebrain. It is continuous with the head of the caudate nucleus. Nucleus accumbens is located in basal forebrain in the preoptic area.

It has an outer shell and an inner core. The inner core is a part of the ventral striatum. Most of the neurons in nucleus accumbens are GABAergic neurons. Olfactory tubercle is a processing center that is common to both the olfactory cortex and ventral striatum. It is also located in the basal area of the forebrain. Corpus striatum receives a number of connections from other areas of the brain.

These connections can be divided into the afferent fibers entering the striatum and the efferent fibers leaving it. A brief detail is given below. The most important input fibers come to striatum from the cortex. It receives projection fibers arising from the pyramidal neurons located in the fifth layer of cortex.

These neurons are glutaminergic neurons. Striatum is considered to have its own microcircuit of neurons in which neurons of one part send and receive fibers from other parts of striatum. Ventral striatum receives fibers from amygdala and hypothalamus. Nucleus accumbens in ventral striatum receives mesolimbic pathway from the ventral tegmental area. Basal ganglia receive fibers from the ventral striatum.

It also receives nigrostriatal fibers from substantia nigra located in midbrain. Efferent fibers from the striatum project mainly to the dorsal pallidum and dorsomedial nucleus of the thalamus. It also sends fibers to globus pallidus and pars reticulata of substantia nigra.

These neurons are inhibitory GABAergic neurons. The blood supply to the striatum is mainly provided via anterior and middle cerebral arteries. The role of the fibers from the thalamus , known as thalamostriate fibers, is not very well understood in humans. Fibers that leave the striatum mostly travel to the main output nuclei of the basal ganglia: the globus pallidus and substantia nigra.

From there, the fibers extend to the thalamus and other areas; projections from the thalamus carry the information back to the cortex. The ventral striatum contains the nucleus accumbens , a nucleus that has been extensively studied for its role in rewarding experiences. The nucleus accumbens--and the ventral striatum as a whole--is associated with reward, reinforcement, and the progression from just experiencing something rewarding to compulsively seeking it out as part of an addiction.

Thus, the ventral striatum is activated when we do--or even just anticipate doing--something we know will be pleasurable. The afferent projections to the ventral striatum come largely from the same places as those of the dorsal striatum although the ventral striatum seems to get more input from the amygdala and hippocampus.

But the involvement of the ventral striatum in reward is most often associated with fibers that travel to the nucleus accumbens from the ventral tegmental area VTA , a dopamine -rich area in the midbrain. This pathway that travels from the VTA to the nucleus accumbens is called the mesolimbic dopamine pathway. It is activated during rewarding experiences e.